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The cannabis industry finds itself in a unique situation. Compared to other regulated industries such as those involving food, dietary supplement and natural products which also combine agriculture, processing, laboratory testing and consumer retail operations, many of the “players” in the cannabis area have only come on board recently. They also do not benefit from federal help. This has resulted in some growing pains as those in each of these various sectors work to gain experience and expertise in real time. The laboratory is faced with a multitude of issues that need to be addressed, ranging from creating profitable compliant businesses involving state licensing and ISO 17025 accreditation requirements and the need to develop and validate their own test methods all with only some of the needed resources such as Reference Materials, Proficiency testing programs, and consistent regulatory requirements.